NBs are nuclear matrix-associated structures of unknown function that contain a number of proteins, including PML, SP100, ISG20, PIC1/SUMO-1, LYSP100, PLZF, INT6, CBP, RB1, RFP and ribosomal protein P ...
SAN DIEGO – All multiple sclerosis patients taking natalizumab (Tysabri) who were diagnosed with progressive multifocal leukoencephalopathy (PML) before symptoms appeared were still alive a year later ...
The promyelocytic leukaemia (PML) gene is translocated in most acute promyelocytic leukaemias and encodes a tumour suppressor protein. PML is involved in multiple apoptotic pathways and is thought to ...
May 31, 2011 — The prognosis of natalizumab (Tysabri; Biogen Idec)–associated progressive multifocal leukoencephalopathy (PML) in patients with multiple sclerosis (MS) appears to be better than for ...
Preparations containing various mixtures of fumaric acid esters are prescribed for psoriasis in several countries, in many cases for off-label use, and are regarded as safe. 1 One such preparation is ...