For the known inflammasomes, new cofactors such as caspase 11 and the NAIPs (NLR family, apoptosis inhibitory proteins) have been described. In addition, inflammasome-independent pathways for the ...
Multicellular organisms, from plants to vertebrates, are constantly subject to environmental, intracellular and extracellular insults. Examples of such insults include pathogens, DNA damage and ...