T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

Regulatory authorities emphasize integrated control strategies, but CAR-T specification setting requires balancing data rigor with regulatory flexibility.

What do cells want to be when they grow up, and how do they get there? Intrigued by these questions, many developmental biologists try to follow the journeys of cells from when they can virtually ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

Scientists have uncovered a new way embryonic cells divide when conventional mechanisms fail. Cell division underpins all ...

How do you currently identify and select cells for further growth, characterization and processing? Many available cell-selection technologies lack the sensitivity necessary to preserve cell health ...

Cell division is an essential process for all life on Earth, yet the exact mechanisms by which cells divide during early embryonic development have remained elusive—particularly for egg-laying species ...

In A Nutshell Egg geometry drives development: The curved shape of a zebrafish egg causes unequal cell divisions, creating larger cells near the animal pole and smaller cells at the margin—a size ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...