During embryonic stem cell (ESC) development, pluripotent stem cells transition from a naïve state into a primed state before they take their first steps toward a lineage commitment. Jacob Hanna, a ...

Cellular aggregates derived from human stem cells in previous studies could not be considered genuinely accurate human embryo models, because they lacked nearly all the defining hallmarks of a ...

The stem cell-based embryo model and actual human embryos share many characteristics but are distinctly different. However, internationally, not everyone agrees on the definitions and what we should ...

Cambridge scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in ...

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...

Technological, ethical and legal issues have limited the understanding of the early stages of embryonic development in humans, despite its importance in basic developmental biology and reproductive ...

Some newly reported clumps of cells growing in lab dishes have been hailed as the closest things to human embryos that scientists have ever made in the lab. These entities are human embryo models — ...

Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

Scientists have grown a scalable new embryo-like model that unshrouds some mysteries of early human development, including blood cell formation, or hematopoiesis—a first for the field. In an article ...

University of Cambridge scientists have used human stem cells to create three-dimensional embryo-like structures that replicate certain aspects of very early human development—including the production ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

Around eight days after fertilization, the human embryo implants in the endometrium (the tissue that lines the uterus). After implantation, it enters a developmental phase that is not well understood ...