Figure 2: Stereo view of the experimental 2.4 Å MIR map for complex A after solvent flattening and histogram matching. Our crystal structure also shows direct and water mediated contacts to the DNA ...

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) is a novel strategy for cancer therapy, but only two inhibitors of NAMPT (FK866 and CHS828) have progressed into clinical trials. This ...

Organizational structure types are the means by which companies group workers, processes and work flows to manage productivity. The three types of organizational structures are functional, divisional ...