From the Wihuri Research Institute (R.O., P.T.K., P.L., M.O.P.) and the Department of Bacteriology and Immunology, University of Helsinki, and Helsinki University ...
Ultralarge von Willebrand factor (vWF) strings are secreted by, and anchored to, stimulated human endothelial cells. A disintegrin and metalloprotease with thrombospondin domains-type 13 cleaves the ...
Spleens were mechanically dissociated through a 100 μm cell strainer (BD Biosciences) and red blood cells were lysed in red blood cell lysis buffer (Morphisto). Peripheral blood was collected via the ...
Cutaneous squamous cell carcinoma (cSCC) is a common form of skin cancer with an estimated 750,000 cases diagnosed annually in the United States. Most cases are successfully treated with a simple ...
After mild traumatic brain injury (TBI), a molecule called complement factor C1q may play a role in the secondary effects of brain injury, such as sleep disruption, epileptic activity, and ...
Copyright: © 2001 Elsevier Ltd. Published by Elsevier Ltd. The clinical picture of HUS related to factor H abnormality has emerged in two ways. The first was through ...
Factor H (FH) is the key regulator of the alternative pathway of complement. The carboxyl‐terminal domains 19–20 of FH interact with the major opsonin C3b, glycosaminoglycans, and endothelial cells.
Background Several studies have identified a central role for the activation of the complement system in the pathogenesis of OA, finding an abnormally high expression and activation of complement in ...
A case–control association study for advanced age-related macular degeneration was conducted to explore several regions of interest identified by linkage. This analysis identified a single nucleotide ...
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