Innate immunity constitutes the body’s first line of defence against invading pathogens. This ancient, evolutionarily conserved system is activated within minutes of encountering foreign agents, ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

Spanish scientists have identified groups of genes associated with a predisposition to the development of ductal ...

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

Dianthus achieved its NASDAQ listing last year via a merger with Magenta Therapeutics. The company is focused on development of a single drug candidate, DNTH-103, which targets the complement system, ...

1 Department of Internal Medicine, Division of Rheumatology, University of New Mexico, Albuquerque, NM 2 Biomedical Research Institute of New Mexico, Albuquerque, NM 3 Department of Molecular Genetics ...

The story of Q32 Bio, a company that develops therapeutics for inflammatory and autoimmune diseases, started two decades ago. That's when V. Michael Holers, MD, a University of Colorado School of ...

CNIO researchers identified complement system genes linked to pancreatic cancer susceptibility and prognosis. Mutations in ...

Cancer immunotherapies, including cancer vaccines, harness and amplify the immune system’s natural ability to detect and attack cancer cells. In this illustration, immune T cells (pink) attach to a ...