Euan Ashley's lab explores the intricate interactions of gene variants. Tiny "typos," or genetic mutations, can sneak into ...

New research finds that retinal diseases thought to map one-to-one to genetic mutations are more complicated than that.

A collaboration including Rice University, Baylor College of Medicine and Texas Children’s Hospital’s Jan and Dan Duncan Neurological Research Institute (NRI) has produced a breakthrough in how to ...

For decades, geneticists have known that most common illnesses are not caused by a single rogue gene but by intricate constellations of DNA variants acting together in specific cells. Now a new ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

Improving the genetic circuits in eukaryotic protein production systems—like human cell lines or Chinese hamster ovaries—has the potential to enhance their value so they may offer not only their own ...

The major histocompatibility complex (MHC) represents a critical gene family in vertebrates that shapes immune recognition and disease resistance through its extraordinary allelic diversity.

The Collaborative Cross (CC) mouse resource has emerged as an indispensable platform for elucidating the genetic basis of complex traits. By combining high levels of genetic diversity from eight ...

An individual’s genetics and their environment both shape their personality. However, opinions differ on the degree to which each of these factors influences personality, and how they contribute to ...

Cystic fibrosis represents one of the most common inherited genetic disorders affecting people of European descent, touching the lives of approximately 30,000 individuals in the United States alone.