The discovery could serve as a starting point for antiviral strategies. A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the ...
Microscope image of human epithelium cells (blue) infected with SARS-CoV-2 (red), showing the virus spreading from one cell to another. LA JOLLA, CA—Despite vaccines and treatments, SARS-CoV-2—the ...
To try to stay ahead of any future pandemics, scientists at Scripps Research in La Jolla are taking a deeper look into the proteins that coronaviruses depend on to survive. And with their findings, ...
This article and associated images are based on a poster originally authored by Cristina Alli, Chiara Soldati, Ottavia Cecchetti, Monica Bisbocci, Sara Pugliese, Mauro Cerretani, Elisa Beghetto, Marta ...
Hosted on MSN
Modified inhibitors show promise against coronaviruses by targeting essential Mac1 protein domain
A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the "macrodomain," found in all coronaviruses such as SARS-CoV-2 and ...
In cooperation with the group led by Professor Michael Kracht at University of Giessen, the team was also able to show that JNK phosphorylates specific serine residues on the N protein. These sites ...
AZoLifeSciences on MSN
Synthetic RNA platform converts viral replication into detectable cellular signals
The technology, called the Viral-Engineered RNA-based Activation System (VERAS), hijacks the virus's own replication machinery to switch on reporter or therapeutic genes precisely in infected cells.
To try to stay ahead of any future pandemics, scientists at Scripps Research in La Jolla are taking a deeper look into the proteins that coronaviruses depend on to survive. And with their findings, ...
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