Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

A team of researchers have identified a fundamental mechanism that links the 24-hour circadian cycle to the precise repair of ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Each cell in our body experiences up to tens of thousands of DNA-damaging events per day, primarily from routine cellular maintenance or exposure to toxins in our environment. Despite the high ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

Alcohol can harm more than your liver and heart—new insights reveal it damages DNA, increasing cancer risk. Experts explain ...

Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what the mechanisms, or the causes behind those specific genetic changes, are.