Passive diffusion plays an essential role in oral absorption of drugs through the gastrointestinal tract, penetration across the blood-brain barrier to reach Central Nervous System disease targets, ...
Congestive heart failure is a disease state distinguished by the regular presence of both renal and hepatic abnormalities in drug handling. One such abnormality involves flaws in the process of drug ...
A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...
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Understanding Particle Drift and its Influence on Oral Drug Absorption Using Flux Tools
In this interview, Karl Box from Pion outlines the benefits of particle drift analysis using flux tools and how this can be used to enhance oral drug absorption in pharmaceutical research. Pion's ...
Purpose Pharmacokinetic considerations in patients who have undergone Roux-en-Y gastric bypass (RYGB) are explored. Summary The prevalence of obesity, especially morbid obesity, has dramatically ...
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