The enzyme transhydrogenase plays a central role in regulating metabolic processes in animals and humans alike. Malfunction can lead to serious disorders. For the first time, structural biologists ...

Within each cell, the power houses called mitochondria continuously break down molecules derived from food to generate energy as well as to produce new molecules that serve as building blocks of cells ...

Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

Researchers have determined the atom-by-atom structure of the fermentation enzyme phosphoketolase by cryogenic electron microscopy. They identified details that were mistakenly characterized by X-ray ...