The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. A research group has demonstrated that overexpression of ...

A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

King Abdullah University of Science & Technology (KAUST)Mar 19 2025 For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

Scientists at the University of Leicester have captured the first detailed "molecular movie" showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life. A new study from King ...