On the left are three forms of the same RNA molecule, which is stabilised into a single form (on the right) by mitoxantrone. Ribonucleic acids (RNAs) serve as messengers between DNA and protein ...

Acetylation of various RNA in cells using dCas13-eNAT10 fusion protein. Utilizing the CRISPR-Cas13 system, which can precisely target specific RNA through guide RNA, a dCas13-eNAT10 fusion protein was ...

CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage. Type V CRISPR-Cas (Cas12) systems, in particular, ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

Immunologists from the Institute have been the first to uncover a role for a family of RNA binding proteins in the function of regulatory T cells in the immune system. As their name suggests, ...

Chemical structure of guanine, showing its double-ring purine structure and the functional groups involved in hydrogen bonding with cytosine. (Image: Public Domain) Guanine has the chemical formula ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

About 95 % of human genes can produce different RNAs through a process called 'alternative splicing'. If you have ever read about cells, genes or DNA, you must have heard about RNA also. Chemically, ...

Kaushik Chanda is a postdoctoral researcher at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology (Scripps Research). He studies how long non-coding RNAs drive structural ...