When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...

New research shows bacteria form distinct species and maintain cohesion through frequent DNA exchange via homologous recombination. When Kostas Konstantinidis proved that many microbes -- like plants ...

A whole-genome sequencing approach shows early promise over current commercial methods for identifying more patients likely to benefit from PARP ...

Comparison of a 3-component genomic instability score to individual biomarker scores in classifying homologous recombination deficiency. The relationship between tumor mutational burden (TMB) and ...

Targeting ALKBH5 with cisplatin-Ga nanodrug to investigate platinum sensitivity in resistant ovarian cancer through m6A-dependent mechanisms. Intermittent PARP inhibitor regimen in ovarian cancer ...