Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-β plaques and Tau tangles in brain tissues. Recent studies indicate that aberrant splicing and increased level of intron ...
Muscle stem cells, the reserve stem cell in the skeletal muscles, are responsible for muscle repair after damage. They are the 'regenerative medicine' to cure muscle diseases and muscle damages. In a ...
Figure 1: H3B-8800 modulates splicing of WT and mutant SF3B1 spliceosomes in vitro and preferentially kills SF3B1-mutant cells. Figure 2: H3B-8800 modulates splicing and selectively kills SF3B1-mutant ...
Scientists have discovered non-coding RNA has a novel role to fine-tune gene expressions during stress recovery, getting closer to uncovering a 30-year-old nuclear mystery. Scientists have discovered ...
Examples of intron retention events in circRNAs and their frequency and length distribution. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert ...
The opportunistic pathogen Candida albicans grows in two forms: yeast and filament. The latter state contributes to the severity of infections, and elevated temperature promotes this morphological ...
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