Figure 1: cDNA microarray analysis of DNA copy-number changes. Figure 3: Genome-wide mapping of DNA copy-number variation for breast cancer cell line BT474. Figure 4: High-resolution analysis of ...

A microarray experiment involves several steps, including spotting complementary DNA, extracting RNA, labeling the probe, hybridizing, scanning and analyzing images. Each step introduces variability, ...

The main steps involved and limitations of microarray analysis will be encountered. Two stages can be distinguished in microarray experiments: a pre-microarray experiment phase (tissue handling) and ...

In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

Yes, many are attracted to next-generation sequencing, but loyalty to chip-based phenotyping has its rewards, particularly in screens of large sample sets. The microarray, the legacy technology for ...

To identify differentially expressed genes and scan candidate molecular markers in nasopharyngeal carcinoma (NPC). We constructed four subtracted cDNA libraries using suppression subtractive ...

Reviewed by Dr. Tomislav Meštrović, MD, Ph.D. The microarray is a recently developed technology used in cancer research and in the pharmacological treatment of other diseases such as oral lesions. In ...

For 20 years, DNA microarrays have been the go-to method for revealing patterns of gene expression. But as the price of next-generation sequencing continues to fall, RNA sequencing (RNA-seq) has ...