This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

In the mutation accumulation experiment, amoebae were allowed to reproduce until they formed a visible plaque, and then one was picked at random and carried to a new plate where it was allowed to ...

James is a published author with multiple pop-history and science books to his name. He specializes in history, space, strange science, and anything out of the ordinary.View full profile James is a ...

In the 1940s, the famous Luria–Delbrück experiment showed that bacteria evolve resistance to drugs they'd never encountered thanks to a random mutational process. When you purchase through links on ...

A single microscopic change in our DNA can permanently alter how the brain is built, locking in developmental problems that no amount of later effort can fully undo. Researchers are now tracing how ...

One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs ...