Interacting proteins tend to have similar functions, influencing the same organismal traits. Interaction networks can be used to expand the list of candidate trait-associated genes from genome-wide ...
Van den Heuvel et al. show that lesion-network mapping (LNM)-derived circuits converge across disorders and argue that this convergence reflects a fundamental methodological limitation of LNM. We ...
The study of focal brain lesions has traditionally been used to map neurologic symptoms to specific regions; however, many neurologic and psychiatric symptoms correspond more closely to networks of ...
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