Dynamic remodeling of the endomembrane system is a core biological process essential for maintaining cellular compartmentalization and homeostasis. Proteins enriched in intrinsically disordered ...

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...

In mammalian cells, besides nuclei, mitochondria are the only semi-autonomous organelles possessing own DNA organized in the form of nucleoids. While eukaryotic nuclear DNA compaction, chromatin ...

Researchers led by Prof. XU Zhiheng from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, revealed the important roles of POSH phase separation and its ...

Crystallization is a well-explored natural phenomenon where atoms or molecules arrange themselves into highly organized solid forms called crystals. This phenomenon has been widely utilized across ...

Genetic engineers can design and assemble sophisticated gene circuits to program cells with new functions, but important signaling molecules can become diluted as these cells grow and divide, causing ...