Protein detection and quantification are daily occurrences both in research and diagnostic laboratories. Also, follow-ups of therapeutic treatments and prognoses have grown to rely more and more on ...

The sequencing phase of the human genome project is now near completion, but then what? An even harder challenge remains — to identify the structures and functions of all proteins encoded in the ...

Protein microarrays are one aspect of highly automated, large-scale biological screening technologies, the other is nucleic acid arrays. As DNA arrays reveal their origin in Southern blotting ...

Planar waveguide (PWG) technology (right) has the advantage over conventional epifluorescence excitation (left) for surface-confined assays in that only surface-bound fluorphores respond to the ...

The hybridization of analytes in a single sample to thousands of different specified targets simultaneously on a microarray has become central to genomics research and is now being applied in the ...

Wildlife biologist Marissa Irwin had no idea that cells in her body had gone haywire. In response to scrambled protein signaling pathways, certain cells turned cancerous and grew into tumors that took ...

A phase I/II study of αGalactosylceramide-pulsed dendritic cells in patients with advanced or recurrent non-small cell lung cancer No significant financial relationships to disclose. This is an ASCO ...

Protein microarrays are emerging as one of the most active areas in biotechnology today. Steady advances are overcoming initial skepticism as to their feasibility and utility. Industry sources project ...

Translational cell study exploring the role of estrogen receptor β expression as a predictive and/or prognostic factor in breast cancer patients No significant financial relationships to disclose.

As illustrated by Dr. Carl Borrebaeck, [4] of Lund University, Sweden, bioarrays may be based on proteins or on affinity reagents. Defined sets of proteins, such as autoantigens, are spotted on ...