Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

Complex sugar-protein molecules that sense external messages to help a cell grow or respond to its environment can now be ...

Heterotrimeric G proteins, comprising Gα, Gβ and Gγ subunits, are central to the transduction of extracellular signals into precise intracellular responses in plants. These proteins not only regulate ...

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...

Cells that are about to die send a signal to an executioner protein, but sometimes, those cells can fight back and regenerate ...

A protein essential to the human body for managing energy and regulating appetite relies on a partner protein, according to new research, and the findings could help researchers better understand ...

Alzheimer's disease (AD) is a serious neurodegenerative disease largely affecting older adults. Apart from age, it also shows ...

Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at the University of Massachusetts Amherst, could have applications beyond ...