Psilocybin could treat depression via a non-hallucinogenic receptor

Psychedelics, psychoactive substances that alter people's perceptions, mood and thought patterns, have recently shown promise ...

In Pursuit of a Psychedelic Without the Hallucination

P silocybin—the psychedelic ingredient found in some “magic” mushrooms—has shown a lot of promise for treating depression and ...
Medscape

Surplus of Serotonin Receptors May Explain Failure of Antidepressants in Some Patients

January 18, 2010 — Individuals with treatment-resistant depression tend to have the G/G genotype associated with higher levels of 5-HT 1A autoreceptors, and turning off some of those autoreceptors ...

How stress hormone receptors alter the brain and behavior: Zebrafish study provides insights

Stress, the body's natural response to different types of challenges and daily problems, is an inherently harmless state ...

Schizophrenia-linked genetic variant renders key brain receptor completely unresponsive to both natural and therapeutic compounds

A rare genetic variant found in families affected by schizophrenia completely abolishes the function of TAAR1, an emerging drug target for psychiatric disorders. The C182F mutation causes a 40% ...