Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Characteristics of BMS-817399 that could influence the potential utility of the ...

We describe general organic solvent solubility correlations derived from methodology that analyzed 63 240 pieces of automation-enabled solubility data of pharmaceutically relevant compounds and ...

BASF and top universities jointly develop new process improving the bioavailability of active ingredients. The Supersonic spray-drying process yields stable and soluble amorphous nanoparticles. In ...

On the other hand, it is well known that injectable homogeneous liquid formulations supply high doses of drug in small volumes, and thus, the solubility of drugs and other formulation components is ...

Industry is adapting to the increasing complexity and poor solubility and bioavailability of molecules in the pipeline. Poor solubility and low bioavailability have hindered the development pipeline ...

High-concentration injectable formulations present unique challenges. Poor solubility issues are often associated with small-molecule APIs formulated for oral administration. Solubility is also ...