Once in every cell cycle microtubules become organized into a bipolar spindle that segregates the replicated chromosomes to the two daughter cells 1,2. Two models, which are not mutually exclusive, ...

Scientists have gained new insight into the formation of the spindle, which is the molecular machine that divides up genetic material prior to cell division. Their work focuses on the motor protein, ...

The findings shed light on the mechanisms behind "self-organization" - an essential characteristic of biological structures. Organisms are composed of a variety of structures including muscles, ...

Cambridge, Mass. - April 26, 2012 - The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests, according to ...

The orientation of cell division is tightly regulated to ensure proper tissue morphogenesis and to prevent cancerous growth. Cell division can be symmetric resulting in two equal daughter cells and ...

Researchers have identified a novel protein that plays a crucial role in the formation of the mitotic spindle, which is essential for correct segregation of a full set of chromosomes to each daughter ...