Seattle will likely be too tough for the 49ers, and Caleb Williams and the Bears can't expect the Rams to fold like the Packers did.

Tipoff is at 6:30 p.m. ET from Mackey Arena. The Boilermakers are 10.5-point favorites per the latest Purdue vs. Iowa odds, while the over/under for total points is 142.5. Before making any Iowa vs. Purdue picks, check out the men's college basketball predictions and betting advice from the SportsLine Projection Model.

What is the point spread for the Bears vs Rams game? What is the moneyline for the divisional round matchup?Start the day smarter. Get all the news you need in your inbox each morning. What is the over/under (point total) for the NFL playoff game?

Learn how to evaluate a company's financial health by understanding economic spread, which compares return on invested capital to weighted average cost of capital.

With all the injuries, the biggest winners of the wild-card round may be the teams that didn't play. The Seahawks and Broncos didn't lose any key players over the weekend, and each could have a player return from IR as Denver linebacker Drew Sanders and Seattle tight end Elijah Arroyo seem to be tracking toward playing this weekend.

Ahead of the College Football Playoff National Championship, Indiana is a 7.5-point favorite over Miami (FL), and the over/under is 48.5 points, according to the DraftKings Sportsbook on Monday morning. The Hoosiers' moneyline odds are -325, while the Hurricanes are +260 underdogs on the moneyline.

Understand the market-maker spread as the price gap between buying and selling offers by market makers, and how it compensates for market-making risks.