A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as ...

Constructed image from spatial transcriptomics slides measuring gene expression in tissues. This shows the developing upper limb, including the developing hand and digits. Each spot represents a ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling-aa ...

A pair of proteins could contribute to the development of healthy, strong bones by directing early cell movement and blood vessel generation. A pair of proteins, YAP and TAZ, has been identified as ...

In a study published in Cell Research, researchers have identified a fibrous-layer resident subpopulation of P-SSCs labeled ...

If you have ever broken a bone, you quickly learn two things: it hurts a lot, and bones are living tissue that takes time to heal, but they do heal. A fractured femur, for instance, may take six ...

Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation, a new study has found.

Stem cells form the backbone of many cell-based therapies due to their unique properties, including the ability to self-renew and differentiate to many cell types. Multiple cell therapies deliver ...