Computational tool incorporates transcriptome size to improve RNA-seq analysis

To get more out of RNA-seq analysis, scientists at St. Jude Children's Research Hospital created ReDeconv, an algorithmic ...
Baylor College of Medicine

Baylor researchers develop and validate clinical diagnostic RNA sequencing test

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...
GEN

Direct RNA Sequencing Supports Novel Discoveries in RNA Biology

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

Scientists transform enigmatic cell structures into devices for recording RNA activity

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and ...
EurekAlert!

Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...
ascopubs.org

Discovering Novel and Unique Saliva and Serum miRNA and mRNA Signatures for Oral Cancer Detection Using Whole Transcriptome and Small Non-Coding RNA Sequencing: Prediction of ...

We identified twelve novel saliva and serum miRNAs and a panel of unique miRNA and mRNA signatures, significantly differentially expressed in saliva and serum of OSCC patients versus HC ...