Retroviral vectors have induced subtle clonal skewing in many gene therapy patients and severe clonal proliferation and leukemia in some of them, emphasizing the need for comprehensive integration ...
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Figure 1: Workflow of genome-wide integrome studies based on nrLAM-PCR, GS FLX sample preparation and sequencing, and bioinformatical data mining. At this time, there are several commercial sequencing ...
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