About one in five patients with cancer who undergo genetic testing are incidentally found to have mutations in their blood ...
For patients with primary solid tumors receiving cancer therapy, clonal hematopoiesis of indeterminate potential is associated with an increased risk for CVD.
Blood cancer is an umbrella term for a variety of diseases that affect the blood, bone marrow and lymphatic system. Like most ...
The presence of clonal hematopoiesis of indeterminate potential (CHIP) was linked to a 27% higher risk of heart failure (adjusted hazard ratio [aHR] 1.27). The association was mainly driven by ...
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Why Some People Resist Blood Cancer Despite Risky Mutations
Researchers identified a rare genetic variant that weakens MSI2 activity in blood stem cells, slowing clonal hematopoiesis ...
A newly identified and rare genetic variant slows the growth of mutated blood stem cells and reduces the risk of leukemia.
Hyperthermic Intraperitoneal Chemotherapy in Platinum-Sensitive Recurrent Ovarian Cancer: A Randomized Trial on Survival Evaluation (HORSE; MITO-18) Clonal hematopoiesis (CH) has been associated with ...
A Systematic Review and Meta-Analysis on the Predictive Value of Cell-Free DNA–Based Androgen Receptor Copy Number Gain in Patients With Castration-Resistant Prostate Cancer Age and exposure to ...
In a recent study published in the journal Nature Genetics, a team of researchers from the United Kingdom (U.K.) and the United States (U.S.) analyzed whole blood samples from a large cohort of U.K.
Antigen-driven selection has been implicated in the pathogenesis of monoclonal gammopathies. Patients with Gaucher’s disease have an increased risk of monoclonal gammopathies. Here we show that the ...
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