Figure 1: Assay with optical tweezers for assessing the mechanistic cycle of NS3. To follow NS3-catalysed unwinding, we flow NS3 (1–90 nM) and ATP (0.05–1 mM) together in buffer U (see Methods). We ...
Thomas J. Chambers, Ronald C. Weir, Arash Grakoui, David W. McCourt, J. Fernando Bazan, Robert J. Fletterick, Charles M. Rice Proceedings of the National Academy of ...
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