Collagen is the most abundant protein in the human body and has an important role in healthy tissue as well as in a range of prevalent diseases. Medical research and diagnostics hence call for means ...

Scientists organize millions of proteins by shape, as predicted by AI, revealing 700,000 new families and some shapes unique to humans.

Proteins are among the most important molecular building blocks of life. They are chains of amino acids assembled in our cells by ribosomes, the molecular "protein factories" of our bodies. The ...

Researchers have engineered a next-generation glutamate sensor, iGluSnFR4, capable of detecting the faintest incoming ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

In a study published in Nature Methods on December 2, a research team led by Profs. Xu Tao and Ji Wei from the Institute of Biophysics of the Chinese Academy of Sciences has developed a ...

Protein aggregation exhibits a dual role in biology, especially in neural systems. While pathogenic aggregates of proteins such as Aβ, tau, and α-synuclein ...