Frontiers

Celline: a flexible tool for one-step retrieval and integrative analysis of public single-cell RNA sequencing data

Single-cell RNA sequencing (scRNA-seq) has generated a rapidly expanding collection of public datasets that provide insight into development, disease, and therapy. However, researchers lack an ...
IEEE

sigRGCN: A Robust Residual Graph Convolutional Network for scRNA-Seq Data Clustering

Abstract: Clustering is a crucial step in single-cell RNA sequencing (scRNA-seq) data analysis, facilitating the discovery of new cell types and the grouping of similar cells. Recently, graph ...
GitHub

ManagedCode.Umap

This is a modernised ManagedCode-maintained reimplementation of the JavaScript version, which was based upon the Python version. "Uniform Manifold Approximation and Projection (UMAP) is a dimension ...
eLife

Gene regulatory mechanisms guiding bifurcation of inhibitory and excitatory neuron lineages in the anterior brainstem

This work is a important resource for hypothesis testing of candidate upstream transcriptional regulatory factors that control the spatiotemporal expression of selector genes and their targets for ...
eLife

Gene regulatory mechanisms guiding bifurcation of inhibitory and excitatory neuron lineages in the anterior brainstem

The authors provide valuable insights into the candidate upstream transcriptional regulatory factors that control the spatiotemporal expression of selector genes and their targets for GABAergic vs ...
GitHub

UMAP (Uniform Manifold Approximation and Projection) in Rust

This repository contains a Rust implementation of UMAP (Uniform Manifold Approximation and Projection), a dimensionality reduction algorithm that preserves both the local and global structure of data.
gut.bmj

Single-cell multimodal analysis reveals the dynamic immunopathogenesis of HBV-ACLF progression

3 Transplantation Center, The Third Xiangya Hospital, Central South University, Changsha, China Background Acute-on-chronic liver failure (ACLF) is a life-threatening syndrome involving dysfunction of ...
HealthTech

Perturb-Seq in Practice: Dissecting Gene Function with CRISPR + scRNA-Seq

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...
GEN

Systemic Sclerosis Organ Damage Revealed Through scRNA-Seq

Systemic sclerosis (SSc) is a rare autoimmune disease that can harden the skin, impair blood flow, and damage internal organs such as the lungs and kidneys. But no two patients experience the disease ...
C&EN

scGANSL: Graph Attention Network with Subspace Learning for scRNA-seq Data Clustering

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.jcim.5c00731. Comparison of model complexity between scGANSL and other ...
TechCrunch

Microsoft CEO says up to 30% of the company’s code was written by AI

During a fireside chat with Meta CEO Mark Zuckerberg at Meta’s LlamaCon conference on Tuesday, Microsoft CEO Satya Nadella said that 20% to 30% of code inside the company’s repositories was “written ...