During the British Industrial Revolution of the late eighteenth and early nineteenth centuries, the United Kingdom experienced an unprecedented time of innovation, technological advancement, and ...

Complement 3 glomerulopathy (C3G) is a rare kidney disease that affects your body’s innate immune system (complement system). Complement 3 glomerulopathy (C3G) is a kidney disease that’s caused by ...

ARO-C3 treatment led to deep and sustained reductions in alternative pathway complement activity and proteinuria. ARO-C3, an investigational RNA interference-based therapy targeting hepatic expression ...

In myasthenia gravis, complement plays a big role in what happens to the muscle end of the neuromuscular junction, explains Miriam Freimer, MD, an author on 5 abstracts presented at the recent 15th ...

Do you find yourself nagging your partner about things they simply don't seem to care about, while they do the same to you? The solution isn't trying to change each other. Instead, it's learning to ...

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that ...

Findings suggest that the complement system plays a role in the onset of acute kidney injury in critically ill patients. Urinary Ba, a fragment of complement factor B, may be a biomarker and mediator ...

While the chef is busy dealing with an oven that’s on the fritz, it’s up to you to put together the pairings for tonight’s nine-course menu. Every clue below has a one-word answer; as a hint, the ...

The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their ...

The alternative complement pathway plays a key role in the pathogenesis of IgA nephropathy. Iptacopan specifically binds to factor B and inhibits the alternative pathway. In this phase 3, double-blind ...

Leadership is about much more than issuing orders or delegating tasks. One of your most essential roles as a leader is to serve as a role model. Your team is constantly observing how you conduct ...