Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells have already transformed the treatment of blood cancers. Yet, despite their ...

A team of leading clinical research scientists from the Departments of Psychiatry and Dermatology at the Icahn School of ...

Takeda ( TSE:4502/NYSE:TAK) today announced that the U.S. Food and Drug Administration (FDA) accepted its New Drug Application (NDA) and granted Priority Review for oveporexton (TAK-861) for the ...

Immunotherapy that blocks microglial Fcγ receptors prevents dopaminergic neuron loss in Parkinson’s disease, revealing a potential new strategy.

The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo. Deleting a single ...

We thank Profs. Jeffrey V. Ravetch (the Rockefeller University) and Fubin Li (Shanghai Jiao Tong University) for providing the Fcgr2b f/f mice. This work was supported by the National Key Research and ...

Please provide your email address to receive an email when new articles are posted on . Use of GLP-1 receptor agonists in diabetes was associated with reduced risk for RA and gout. No reduction in PsA ...

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights ...

Therapeutic antibodies, especially polyclonal antibodies, are indispensable in contemporary medicine for addressing a broad spectrum of conditions, including infectious diseases, autoimmune disorders, ...

Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...

The amount of each of the more than a thousand different glycoproteins in your blood varies widely with the 10 most abundant glycoproteins accounting for 90 percent of the total mass. Finding a ...