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Though phagocytosis is usually associated with bacteria or other small pathogens, cancer cells can also be phagocytosed and thus destroyed by macrophages. However, many cancer cells alter the expression of surface receptors such as CD47 to evade phagocytosis (either upregulating 'don't eat me' or downregulating 'eat me' signals). There are numerous clinical trials testing novel therapeutics that target this phagocytosis blockade. #immunology #immunesystem #phagocytosis #macrophage #premed #bioto
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